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2. El omega-3 en procesos inflamatorios

Samaras N, Samaras D, Chambellan A, Pichard C, Thibault R. Pulmonary Rehabilitation: The Reference Therapy for Undernourished Patients with Chronic Obstructive Pulmonary Disease. Biomed Res Int. 2014;2014:248420.
2.1. Inflamaci�n

Alsaleh A, Crepostnaia D, Maniou Z et al. Adiponectin gene variant interacts with fish oil supplementation to influence serum adiponectin in older individuals. J Nutr. 2013 Jul;143(7):1021-7.
Bannenberg G, Serhan CN. Specialized pro-resolving lipid mediators in the inflammatory response: An update. Biochim Biophys Acta. 2010 Dec;1801(12):1260-73.
Bannenberg GL. Resolvins: Current understanding and future potential in the control of inflammation. Curr Opin Drug Discov Devel. 2009 Sep;12(5):644-58.
Calder PC. Dietary modification of inflammation with lipids. Proc Nutr Soc. 2002 Aug;61(3):345-58.
Calder PC. Fatty acids and inflammation: the cutting edge between food and pharma. Eur J Pharmacol. 2011 Sep;668 Suppl 1:S50-8. doi: 10.1016/j.ejphar.2011.05.085. Epub 2011 Jul 28.
Calder PC. Fatty acids and inflammation: the cutting edge between food and pharma. Eur J Pharmacol. 2011 Sep;668 Suppl 1:S50-8. doi: 10.1016/j.ejphar.2011.05.085. Epub 2011 Jul 28.
Calder PC. Fatty acids and inflammation: the cutting edge between food and pharma. Eur J Pharmacol. 2011 Sep;668 Suppl 1:S50-8. doi: 10.1016/j.ejphar.2011.05.085. Epub 2011 Jul 28.
Calder PC. n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am J Clin Nutr. 2006 Jun;83(6 Suppl):1505S-1519S.
Calder PC. Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology? Br J Clin Pharmacol. 2013 Mar;75(3):645-662.
Calder PC. Polyunsaturated fatty acids, inflammation, and immunity. Lipids 2001;36:10007-24.
Chang HY, Lee HN, Kim W, Surh YJ. Docosahexaenoic acid induces M2 macrophage polarization through peroxisome proliferator-activated receptor γ activation. Life Sci. 2015 Jan 1;120:39-47. doi: 10.1016/j.lfs.2014.10.014.
Cipollina C, Di Vincenzo S, Gerbino S, Siena L, Gjomarkaj M, Pace E. Dual anti-oxidant and anti-inflammatory actions of the electrophilic cyclooxygenase-2-derived 17-oxo-DHA in lipopolysaccharide- and cigarette smoke-induced inflammation. Biochim Biophys Acta. 2014 Mar 2. pii: S0304-4165(14)00085-3.
Ferguson JF, Mulvey CK, Patel PN et al. Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers. Mol Nutr Food Res. 2013 Nov 5.
Heemskerk MM, Dharuri HK, van den Berg SA, J�nasd�ttir HS, Kloos DP, Giera M, van Dijk KW, van Harmelen V. �Prolonged niacin treatment leads to increased adipose tissue PUFA synthesis and anti-inflammatory lipid and oxylipin plasma profile.� J Lipid Res. 2014 Dec;55(12):2532-40. doi: 10.1194/jlr.M051938.
Kew S, Mesa MD, Tricon S, Buckley R, Minihane AM, Yaqoob P. Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on immune cell composition and function in healthy humans. Am J Clin Nutr. 2004 Apr;79(4):674-81.
Lee KW, Blann AD, Lip GY. Effects of omega-3 polyunsaturated fatty acids on plasma indices of thrombogenesis and inflammation in patients post-myocardial infarction. Thromb Res. 2006;118(3):305-12. Epub 2005 Sep 8.
Massaro M, Scoditti E, Carluccio MA, Campana MC, De Caterina R. Omega-3 fatty acids, inflammation and angiogenesis: basic mechanisms behind the cardioprotective effects of fish and fish oils. Cell Mol Biol (Noisy-le-grand). 2010 Feb 25;56(1):59-82.
Massaro M, Scoditti E, Carluccio MA, Montinari MR, De Caterina R. Omega-3 fatty acids, inflammation and angiogenesis: nutrigenomic effects as an explanation for anti-atherogenic and anti-inflammatory effects of fish and fish oils. J Nutrigenet Nutrigenomics. 2008;1(1-2):4-23. Epub 2007 Oct 17.
Mesa Garc�a MD, Aguilera Garc�a CM, Gil Hern�ndez A. Importancia de los l�pidos en el tratamiento nutricional de las patolog�as de base inflamatoria. Nutr Hosp. 2006;21(Suppl.2):30-43.
Raphael W, Sordillo LM. Dietary polyunsaturated Fatty acids and inflammation: the role of phospholipid biosynthesis. Int J Mol Sci. 2013 Oct 22;14(10):21167-88.
Seki H, Sasaki T, Ueda T et al. Resolvins as regulators of the immune system. ScientificWorldJournal 2010;10:818�831.
Sijben JW, Calder PC. Differential immunomodulation with long-chain n-3 PUFA in health and chronic disease. Proc Nutr Soc. 2007 May;66(2):237-59.
Skulas-Ray AC, Kris-Etherton PM, Harris WS et al. Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia. Am J Clin Nutr. 2011 Feb;93(2):243-52.
Thies F, Miles EA, Nebe-von-Caron G, Powell JR, Hurst TL, Newsholme EA, Calder PC. Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. Lipids. 2001 Nov;36(11):1183-93.
Yates CM, Calder PC, Ed Rainger G. Pharmacology and therapeutics of omega-3 polyunsaturated fatty acids in chronic inflammatory disease. Pharmacol Ther. 2013 Nov 4. pii: S0163-7258(13)00215-5.
2.2. Procesos inflamatorios sist�micos

Llor X. Papel de los l�pidos de la dieta en los mecanismos de inflamaci�n, proliferaci�n, diferenciaci�n y muerte celular en el tracto intestinal. Gastroenterol Hepatol. 2003;26:507-13.
Oz HS, Chen TS, Neuman M. Nutrition intervention: a strategy against systemic inflammatory syndrome. JPEN J Parenter Enteral Nutr. 2009 Jul-Aug;33(4):380-9. Epub 2009 Apr 14.
Sabbatini M, Apicella L, Cataldi M, Maresca I, Nastasi A, Vitale S, Memoli B, Postiglione L, Riccio E, Gallo R, Federico S, Guida B. Effects of a diet rich in N-3 polyunsaturated fatty acids on systemic inflammation in renal transplant recipients. J Am Coll Nutr. 2013;32(6):375-83. doi: 10.1080/07315724.2013.826482.
Undurti N Das. Can essential fatty acids reduce the burden of disease(s)? Lipids Health Dis. 2008;7:9.
2.2.1. Obesidad

Browning LM. n-3 Polyunsaturated fatty acids, inflammation and obesity-related disease. Proc Nutr Soc. 2003 May;62(2):447-53.
Buckley JD, Howe PR. Long-chain omega-3 polyunsaturated fatty acids may be beneficial forreducing obesity-a review. Nutrients 2010;2(12):1212-1230.
Dangardt F, Osika W, Chen Y et al. Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents. Atherosclerosis. 2010 Oct;212(2):580-585.
Howe PR, Buckley JD, Murphy KJ, Pettman T, Milte C, Coates AM. Relationship between erythrocyte omega-3 content and obesity is gender dependent. Nutrients. 2014 May 5;6(5):1850-60. doi: 10.3390/nu6051850.
Huerta AE, Navas-Carretero S, Prieto-Hontoria PL, Mart�nez JA, Moreno-Aliaga MJ. �Effects of α-lipoic acid and eicosapentaenoic acid in overweight and obese women during weight loss.� Obesity (Silver Spring). 2015 Feb;23(2):313-21. doi: 10.1002/oby.20966.
Itoh M, Suganami T, Satoh N, Tanimoto-Koyama K, Yuan X, Tanaka M, Kawano H, Yano T, Aoe S, Takeya M, Shimatsu A, Kuzuya H, Kamei Y, Ogawa Y. Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects. Arterioscler Thromb Vasc Biol. 2007;27;1918-25.
LeMieux MJ, Kalupahana NS, Scoggin S, Moustaid-Moussa N. �Eicosapentaenoic Acid reduces adipocyte hypertrophy and inflammation in diet-induced obese mice in an adiposity-independent manner." J Nutr. 2015 Mar;145(3):411-7. doi: 10.3945/jn.114.202952.
L�pez-Vicario C, Alcaraz-Quiles J, Garc�a-Alonso V, Rius B, Hwang SH, Titos E, Lopategi A, Hammock BD, Arroyo V, Cl�ria J. Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides. Proc Natl Acad Sci U S A. 2014 Dec 30. pii: 201422590.
Periyalil HA, Gibson PG, Wood LG. Immunometabolism in obese asthmatics: are we there yet? Nutrients. 2013 Sep 10;5(9):3506-3530.
Recasens M, Ricart W, Fern�ndez-Real JM. Obesidad e inflamaci�n. Rev Med Univ Navarra. 2004;48(2):49-54.
Rius B, L�pez-Vicario C, Gonz�lez-P�riz A, Mor�n-Salvador E, Garc�a-Alonso V, Cl�ria J, TitosE. Resolution of inflammation in obesity-induced liver disease. Front Immunol. 2012; 3: 257.
White PJ, Mitchell PL, Schwab M, Trottier J, Kang JX, Barbier O, Marette A. Transgenic ω-3 PUFA enrichment alters morphology and gene expression profile in adipose tissue of obese mice: Potential role for protectins. Metabolism. 2015 Feb 3. pii: S0026-0495(15)00036-0. Doi:10.1016/j.metabol.2015.01.017.
2.2.2. S�ndrome metab�lico

Browning LM, Krebs JD, Moore CS, Mishra GD, O'Connell MA, Jebb SA. The impact of long chain n-3 polyunsaturated fatty acid supplementation on inflammation, insulin sensitivity and CVD risk in a group of overweight women with an inflammatory phenotype. Diabetes Obes Metab. 2007 Jan;9(1):70-80.
Simopoulos AP. Dietary Omega-3 Fatty Acid Deficiency and High Fructose Intake in the Development of Metabolic Syndrome, Brain Metabolic Abnormalities, and Non-Alcoholic Fatty Liver Disease. Nutrients 2013;5(8):2901-2923.
Tabbaa M, Golubic M, Roizen MF et al. Docosahexaenoic Acid, inflammation, and bacterial dysbiosis in relation to periodontal disease, inflammatory bowel disease, and the metabolic syndrome. Nutrients 2013;5(8):3299-3310.
2.2.3. Diabetes

Aslan M, Ozcan F, Aslan B et al. LC-MS/MS analysis of plasma polyunsaturated fatty acids in type 2 diabetic patients after insulin analog initiation therapy. Lipids Health Dis. 2013 Nov 6;12(1):169.
Chung HF, Long KZ, Hsu CC, Al Mamun A, Jhang HR, Shin SJ, Hwang SJ, Huang MC. Association of n-3 polyunsaturated fatty acids and inflammatory indicators with renal function decline in type 2 diabetes. Clin Nutr. 2014 Mar 19. pii: S0261-5614(14)00071-5.
Hajianfar H, Paknahad Z, Bahonar A. The effect of omega-3 supplements on antioxidant capacity in patients with type 2 diabetes. Int J Prev Med. 2013 May;4(Suppl 2):S234-8.
Herrera BS, Hasturk H, Kantarci A, Freire MO, Nguyen O, Kansal S, Van Dyke TE. Impact of resolvin E1 on murine neutrophil phagocytosis in type 2 diabetes. Infect Immun. 2015 Feb;83(2):792-801. doi: 10.1128/IAI.02444-14.
Jamilian M, Samimi M, Kolahdooz F, Khalaji F, Razavi M, Asemi Z. Omega-3 fatty acid supplementation affects pregnancy outcomes in gestational diabetes: a randomized, double-blind, placebo-controlled trial. J Matern Fetal Neonatal Med. 2015 Mar 9:1-7.
Mart�n de Santa Olalla L, S�nchez Muniz FJ, Vaquero MP. N-3 fatty acids in glucose metabolism and insulin sensitivity. Nutr Hosp. 2009 Mar-Apr;24(2):113-27.
Shidfar F, Keshavarz A, Hosseyni S et al. Effects of omega-3 fatty acid supplements on serum lipids, apolipoproteins and malondialdehyde in type 2 diabetes patients. East Mediterr Health J. 2008 Mar-Apr;14(2):305-313.
Tang Y, Zhang MJ, Hellmann J et al. Proresolution therapy for the treatment of delayed healing of diabetic wounds. Diabetes. 2013 Feb;62(2):618-27.
Udupa A, Nahar P, Shah S et al. A Comparative Study of Effects of Omega-3 Fatty Acids, Alpha Lipoic Acid and Vitamin E in Type 2 Diabetes Mellitus. Ann Med Health Sci Res. 2013 Jul-Sep; 3(3):442-446.
Virtanen JK, Mursu J, Voutilainen S et al. Serum Omega-3 Polyunsaturated Fatty Acids and Risk of Incident Type 2 Diabetes in Men: The Kuopio Ischaemic Heart Disease Risk Factor Study. Diabetes Care. 2013 Sep 11.
West SG, Hecker KD, Mustad VA, Nicholson S, Schoemer SL, Wagner P, Hinderliter AL, Ulbrecht J, Ruey P, Kris-Etherton PM. Acute effects of monounsaturated fatty acids with and without omega-3 fatty acids on vascular reactivity in individuals with type 2 diabetes. Diabetologia. 2005 Jan;48(1):113-22. Epub 2004 Dec 29.
White PJ, St-Pierre P, Charbonneau A, Mitchell PL, St-Amand E, Marcotte B, Marette A. Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis. Nat Med. 2014 May 11. doi: 10.1038/nm.3549. [Epub ahead of print]
2.3. Procesos inflamatorios delimitados

2.3.1. Artritis reumatoide

Ariza-Ariza R, Mestanza-Peralta M, Cardiel MH. Omega-3 fatty acids in rheumatoid arthritis: an overview. Semin Arthritis Rheum. 1998 Jun;27(6):366-70.
Astorga G, Cubillos A, Masson L, Silva JJ. Active rheumatoid arthritis: effect of dietary supplementation with omega-3 oils. A controlled double-blind trial. Rev Med Chil. 1991 Mar;119(3):267-72.
Bahadori B, Uitz E, Thonhofer R, Trummer M, Pestemer-Lach I, McCarty M, Krejs GJ. omega-3 Fatty acids infusions as adjuvant therapy in rheumatoid arthritis. JPEN J Parenter Enteral Nutr. 2010 Mar-Apr;34(2):151-5.
Caughey GE, James MJ, Proudman SM et al. Fish oil supplementation increases the cyclo oxygenase inhibitory activity of paracetamol in rheumatoid arthritis patients. Complement Ther Med 2010;18:171�174.
Das Gupta AB, Hossain AK, Islam MH, Dey SR, Khan AL. Role of omega-3 fatty acid supplementation with indomethacin in suppression of disease activity in rheumatoid arthritis. Bangladesh Med Res Counc Bull. 2009 Aug;35(2):63-8.
Geusens P, Wouters C, Nijs J, Jiang Y, Dequeker J. Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis. A 12-month, double-blind, controlled study. Arthritis Rheum. 1994 Jun;37(6):824-9.
Gheita T, Kamel S, Helmy N et al. Omega-3 fatty acids in juvenile idiopathic arthritis: effect on cytokines (IL-1 and TNF-a), disease activity and response criteria. Clin Rheumatol. 2012 Feb;31(2):363-366.
Goldberg RJ, Katz J. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain. Pain. 2007 May;129(1-2):210-223.
Hurst S, Zainal Z, Caterson B et al. Dietary fatty acids and arthritis. Prostaglandins Leukot Essent Fatty Acids 2010;82:315�318.
James M, Proudman S, Cleland L. Fish oil and rheumatoid arthritis: past, present and future. Proc Nutr Soc. 2010 Aug;69(3):316-23.
Kjeldsen-Kragh J, Lund JA, Riise T, Finnanger B, Haaland K, Finstad R, Mikkelsen K, F�rre O. Dietary omega-3 fatty acid supplementation and naproxen treatment in patients with rheumatoid arthritis. J Rheumatol. 1992 Oct;19(10):1531-6.
Kremer JM. Clinical studies of omega-3 fatty acid supplementation in patients who have rheumatoid arthritis. Rheum Dis Clin North Am. 1991 May;17(2):391-402.
Lee AL, Park Y. The Association between n-3 Polyunsaturated Fatty Acid Levels in Erythrocytes and the Risk of Rheumatoid Arthritis in Korean Women. Ann Nutr Metab. 2013 Aug 14;63(1-2):88-95.
Lee YH, Bae SC, Song GG. Omega-3 polyunsaturated fatty acids and the treatment of rheumatoid arthritis: a meta-analysis. Arch Med Res. 2012 Jul;43(5):356-362.
Leeb BF, Sautner J, Andel I, Rintelen B. Intravenous application of omega-3 fatty acids in patients with active rheumatoid arthritis. The ORA-1 trial. An open pilot study. Lipids. 2006 Jan;41(1):29-34.
Miles EA, Calder PC. Influence of marine n-3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis. Br J Nutr. 2012 Jun;107 Suppl 2:S171-84.
Norling LV, Perretti M. The role of omega-3 derived resolvins in arthritis. Curr Opin Pharmacol. 2013 Jun;13(3):476-481.
Proudman SM, James MJ, Spargo LD et al. Fish oil in recent onset rheumatoid arthritis: a randomised, double-blind controlled trial within algorithm-based drug use. Ann Rheum Dis. Published online September 30, 2013.
Ruggiero C, Lattanzio F, Lauretani F, Gasperini B, Andres-Lacueva C, Cherubini A. Omega-3 polyunsaturated fatty acids and immune-mediated diseases: inflammatory bowel disease and rheumatoid arthritis. Curr Pharm Des. 2009;15(36):4135-48.
Sperling RI. Dietary omega-3 fatty acids: effects on lipid mediators of inflammation and rheumatoid arthritis. Rheum Dis Clin North Am. 1991 May;17(2):373-89.
Venkatraman JT, Chu WC. Effects of dietary omega-3 and omega-6 lipids and vitamin E on serum cytokines, lipid mediators and anti-DNA antibodies in a mouse model for rheumatoid arthritis. J Am Coll Nutr. 1999 Dec;18(6):602-13.
Wann AK, Mistry J, Blain EJ et al. Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1�-mediated cartilage degradation. Arthritis Res Ther. 2010;12(6):R207.
Xu ZZ, Ji RR. Resolvins are potent analgesics for arthritic pain. Br J Pharmacol. 2011 Sep;164(2):274-277.
2.3.2. Enfermedad inflamatoria intestinal

Almallah YZ, El-Tahir A, Heys SD, Richardson S, Eremin O. Distal procto-colitis and n-3 polyunsaturated fatty acids: The mechanism(s) of natural cytotoxicity inhibition. Eur J Clin Invest. 2000;30:58-65.
Almallah YZ, Ewen SW, El-Tahir A, Mowat NA, Brunt PW, Sinclair TS, Heys SD, Eremin O. Distal proctocolitis and n-3 polyunsaturated fatty acids (n-3 PUFAs): the mucosal effect in situ. J Clin Immunol. 2000 Jan;20(1):68-76.
Almallah YZ, Richardson S, O'Hanrahan T, Mowat NA, Brunt PW, Sinclair TS, Ewen S, Heys SD, Eremin O. Distal procto-colitis, natural cytotoxicity, and essential fatty acids. Am J Gastroenterol. 1998;93:804-9.
Arrizabalga JJ. Manejo nutricional de la enfermedad inflamatoria intestinal. Endocrinol Nutr. 2007;54:151-68.
Bento AF, Claudino RF, Dutra RC et al. Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice. J Immunol. 2011 Aug 15;187(4):1957-69.
Llor X. Papel de los l�pidos de la dieta en los mecanismos de inflamaci�n, proliferaci�n, diferenciaci�n y muerte celular en el tracto intestinal. Gastroenterol Hepatol. 2003;26:507-13.
Marcon R, Bento AF, Dutra RC et al. Maresin 1, a proresolving lipid mediator derived from omega-3 polyunsaturated fatty acids, exerts protective actions in murine models of colitis. J Immunol. 2013 Oct 15;191(8):4288-98.
Mbodji K, Charpentier C, Gu�rin C et al. Adjunct therapy of n-3 fatty acids to 5-ASA ameliorates inflammatory score and decreases NF-?B in rats with TNBS-induced colitis. J Nutr Biochem. 2013 Apr;24(4):700-5.
Ruggiero C, Lattanzio F, Lauretani F, Gasperini B, Andres-Lacueva C, Cherubini A. Omega-3 polyunsaturated fatty acids and immune-mediated diseases: inflammatory bowel disease and rheumatoid arthritis. Curr Pharm Des. 2009;15(36):4135-48.
Sharon P, Stenson WF. Enhanced synthesis of leukotriene B4 by colonic mucosa in inflammatory bowel disease. Gastroenterology. 1984;86:453-60.
Tabbaa M, Golubic M, Roizen MF et al. Docosahexaenoic Acid, inflammation, and bacterial dysbiosis in relation to periodontal disease, inflammatory bowel disease, and the metabolic syndrome. Nutrients 2013;5(8):3299-3310.
Trebble TM, Arden NK, Wootton SA, Calder PC, Mullee MA, Fine DR, Stroud MA. Fish oil and antioxidants alter the composition and function of circulating mononuclear cells in Crohn disease. Am J Clin Nutr. 2004;80:1137-44.
Turner D, Shah PS, Steinhart AH, Zlotkin S, Griffiths AM. Maintenance of remission in inflammatory bowel disease using omega-3 fatty acids (fish oil): A systematic review and meta-analyses. Inflamm Bowel Dis. 2010 Jun 17.
Uchiyama K, Nakamura M, Odahara S et al. N�3 polyunsaturated fatty acid diet therapy for patients with inflammatory bowel disease. Inflamm Bowel Dis 2010;16:1696�1707.
Zhang R, He GZ, Wang YK, Zhou KG, Ma EL. Omega-3 polyunsaturated fatty acids inhibit the increase in cytokines and chemotactic factors induced in vitro by lymph fluid from an intestinal ischemia-reperfusion injury model. Nutrition. 2015 Mar;31(3):508-14. doi: 10.1016/j.nut.2014.10.015.
2.3.3. Periodontitis

Elkhouli AM. The efficacy of host response modulation therapy (omega-3 plus low-dose aspirin) as an adjunctive treatment of chronic periodontitis (clinical and biochemical study). J Periodontal Res. 2011 Apr;46(2):261-8.
El-Sharkawy H, Aboelsaad N, Eliwa M et al. Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 fatty acids and low-dose aspirin. J Periodontol. 2010;81:1635-1643.
Mustafa M, Zarrough A, Bolstad AI et al. Resolvin D1 protects periodontal ligament. Am J Physiol Cell Physiol. 2013 Sep;305(6):C673-9.
Tabbaa M, Golubic M, Roizen MF et al. Docosahexaenoic Acid, inflammation, and bacterial dysbiosis in relation to periodontal disease, inflammatory bowel disease, and the metabolic syndrome. Nutrients 2013;5(8):3299-3310.
2.3.4. Otros

Depner CM, Philbrick KA, Jump DB. Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis. J Nutr. 2013 Mar;143(3):315-323.
Hsiao HM, Sapinoro RE, Thatcher TH et al. A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation. PLoS One. 2013;8(3):e58258.
Jafari T, Feizi A, Askari G, Fallah AA. �Parenteral immunonutrition in patients with acute pancreatitis: a systematic review and meta-analysis.� Clin Nutr. 2015 Feb;34(1):35-43. doi: 10.1016/j.clnu.2014.05.008.
Svahn SL, Grahnemo L, P�lsd�ttir V, Nookaew I, Wendt K, Gabrielsson B, Sch�le E, Benrick A, Andersson N, Nilsson S, Johansson ME, Jansson JO. Dietary Polyunsaturated Fatty Acids Increase Survival and Decrease Bacterial Load during Septic Staphylococcus aureus Infection and Improve Neutrophil Function in Mice. Infect Immun. 2015 Feb;83(2):514-21. doi: 10.1128/IAI.02349-14.






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