Studies

Pediatría

Alergias

Asma

Desarrollo neurológico en el feto e infancia

Collado MC, Santaella M, Mira-Pascual L, Martínez-Arias E, Khodayar-Pardo P, Ros G, Martínez-Costa C. Longitudinal Study of Cytokine Expression, Lipid Profile and Neuronal Growth Factors in Human Breast Milk from Term and Preterm Deliveries. Nutrients. 2015 Oct 19;7(10):8577-91.

Almeida DM, Jandacek RJ, Weber WA, McNamara RK. Docosahexaenoic acid biostatus is associated with event-related functional connectivity in cortical attention networks of typically developing children. Nutr Neurosci. 2015 Oct 13.

Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG. Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome. Nat Genet. 2015 May 25. doi: 10.1038/ng.3311.

Sherry CL, Oliver JS, Marriage BJ. Docosahexaenoic acid supplementation in lactating women increases breast milk and plasma docosahexaenoic acid concentrations and alters infant omega 6:3 fatty acid ratio. Prostaglandins Leukot Essent Fatty Acids. 2015 Apr;95:63-9. doi: 10.1016/j.plefa.2015.01.005. FULL TEXT

Strickland AD. Prevention of cerebral palsy, autism spectrum disorder, and attention deficit - Hyperactivity disorder. Med Hypotheses. 2014 May;82(5):522-8.

Williams JJ, Mayurasakorn K, Vannucci SJ et al. N-3 fatty acid rich triglyceride emulsions are neuroprotective after cerebral hypoxic-ischemic injury in neonatal mice. PLoS One. 2013;8(2):e56233. doi: 10.1371/journal.pone.0056233. Epub 2013 Feb 20. FULL TEXT

Morse NL. Benefits of docosahexaenoic acid, folic acid, vitamin D and iodine on foetal and infant brain development and function following maternal supplementation during pregnancy and lactation. Nutrients. 2012;4(7):799-840. FULL TEXT

Zhang W, Hu X, Yang W, Gao Y, Chen J. Omega-3 polyunsaturated fatty acid supplementation confers long-term neuroprotection against neonatal hypoxic-ischemic brain injury through anti-inflammatory actions. Stroke. 2010 Oct;41(10):2341-7. FULL TEXT

Gil-Campos M, Dalmau Serra J; Comité de Nutrición de la Asociación Española de Pediatría. [Importance of docosahexaenoic acid (DHA): Functions and recommendations for its ingestion in infants]. An Pediatr (Barc). 2010 Sep;73(3):142.e1-8. Epub 2010 Jun 8. FULL TEXT

Carlson SE. Docosahexaenoic acid supplementation in pregnancy and lactation. Am J Clin Nutr. 2009 Feb;89(2):678S-84S. Epub 2008 Dec 30. FULL TEXT

Levant B, Radel JD, Carlson SE. Decreased brain docosahexaenoic acid during development alters dopamine-related behaviors in adult rats that are differentially affected by dietary remediation. Behav Brain Res 2004;152:49-57.

Levant B, Radel JD, Carlson SE. Decreased brain docosahexaenoic acid during development alters dopamine-related behaviors in adult rats that are differentially affected by dietary remediation. Behav Brain Res 2004;152:49-57.

Valenzuela A, Nieto S. Ácido docosahexaenoico (DHA) en el desarrollo fetal y en la nutrición materno-infantil. Rev Med Chile. 2001;129:1203-11. FULL TEXT

Desarrollo visual y cognitivo en la infancia

Fu Z, Lofqvist CA, Shao Z, Sun Y, Joyal JS, Hurst CG, Cui RZ, Evans LP, Tian K, SanGiovanni JP, Chen J, Ley D, Hansen Pupp I, Hellstrom A, Smith LE. Dietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin. Am J Clin Nutr. 2015 Apr;101(4):879-88. doi: 10.3945/ajcn.114.099291.

Colombo J, Carlson SE, Cheatham CL, Shaddy DJ, Kerling EH, Thodosoff JM, Gustafson KM, Brez C. Long-term effects of LCPUFA supplementation on childhood cognitive outcomes. Am J Clin Nutr. 2013 Aug;98(2):403-12. FULL TEXT

Kuratko CN, Barrett EC, Nelson EB et al. The relationship of docosahexaenoic acid (DHA) with learning and behavior in healthy children: a review. Nutrients. 2013 Jul 19;5(7):2777-2810. FULL TEXT

Lassek WD, Gaulin SJ. Maternal milk DHA content predicts cognitive performance in 28 nations. Matern Child Nutr 2013; Jun 25 doi: 10.1111/mcn.12060

Richardson AJ, Burton JR, Sewell RP et al. Docosahexaenoic acid for reading, cognition and behavior in children aged 7-9 years: a randomized, controlled trial (the DOLAB Study). PLoS One 2012;7(9):e43909. FULL TEXT

Jacques C, Levy E, Muckle G et al. Long-term effects of prenatal omega-3 fatty acid intake on visual function in school-age children. J Pediatr 2011;158(1):83-90. FULL TEXT

Birch EE, Carlson SE, Hoffman DR et al. The DIAMOND (DHA Intake And Measurement Of Neural Development) Study: a double-masked, randomized controlled clinical trial of the maturation of infant visual acuity as a function of the dietary level of docosahexaenoic acid. Am J Clin Nutr. 2010 Apr;91(4):848-59. FULL TEXT

Heird WC, Lapillonne A. The role of essential fatty acids in development. Annu Rev Nutr. 2005;25:54971.

Uauy R, Hoffman D, Peirano P, Birch D, Birch E. Essential fatty acids in visual and brain development. Lipids. 2001;36:885-95.

Cunnane S. Fatty acid profiles of maternal adipose tissue in relation to infant development. Brit J Nutr 1999; 82: 253-4.

Uauy R, Mena P, Valenzuela A. Essential fatty acids as determinants of lipid requirements in infants, children and adults. Eur J Clin Nutr 1999; 53: 66-77

Birch E, Hoffman D, Uauy R. Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr Res 1998; 44: 1-9.

Agostoni C, Trojan S, Bellú R, Riva E, Brunezze M, Giovannini M. Developmental quotient at 24 months and fatty acid composition of diet in early infancy: a follow-up study. Arch Dis Child. 1997;76:421-4. FULL TEXT

Sastry P. Lipids in the nervous system: Compo sition and metabolism. Prog Lipid Res. 1985;24:69-176.

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